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China's Ning refreshes national record at speed skating World Cup******

WASHINGTON, Dec. 5 (Xinhua) -- Ning Zhongyan of China continued to show good form in the 2021-22 season International Skating Union (ISU) speed skating World Cup series, winning a silver with a national record time of one minute and 41.38 seconds in the men's 1,500m in Salt Lake City, the United States on Saturday.。

This is the third medal at as many World Cups for the 22-year-old after his two victories over the distance in the previous stops. The World Cup leader was 0.23 seconds behind his pair and eventual winner Joey Mantia of the United States, and slicing nearly a second off his own record made him excited.。

"I'm really happy with my time," Ning told the ISU official website. "To skate a personal best, and also to break the Chinese record again."

Skating on home ice, Mantia crossed the line with a personal best time of 1:41.15 for the gold, only 0.98 seconds short of the world record. World champion Thomas Krol of the Netherland came third in 1:41.892.。

"(I was) hoping to get under the 1.41 mark and to be in the 1.40, but I'm very happy with it. It's consistent. And it's a huge confidence builder going into the Olympics," Mantia said.。

In the women's middle distance race, Olympic bronze medalist Miho Takagi of Japan triumphed in the 1,000m competition in 1:11.83, only 0.22 seconds short of Brittany Bowe's world record. Dutch Jutta Leerdam took the silver 0.42 seconds behind. The American world record holder Bowe had to settle for a third place finish in 1:12.608 after two wins this season and continued to lead the World Cup standings.。

Tagaki was close to another gold in team pursuit, but her sister Nana fell in the final lap and Canada took gold in 2:52.390, followed by the Netherlands (2:52.692) and Russia (2:56.220).。

Also on Saturday, Andzelika Wojcik claimed the gold in a Polish national record time of 36.775 seconds, edging Russian world champion Angelina Golikova by 0.01 second for her maiden World Cup victory in women's 500m. Olga Fatkulina had her first podium finish this season in 36.937 seconds.。

The men's mass start, Bart Swings of Belgium had a convincing victory ahead of Viktor Hald Thorup of Denmark and Ruslan Zakharov of Russia. Enditem。

Uganda gears up for FIFA World Cup qualifier against Kenya******

KAMPALA, Nov. 8 (Xinhua) -- Uganda coach Milutin Sredojevic has named his final squad for a 2022 FIFA World Cup qualifier against Kenya on November 11.。

Sredojevic told Xinhua on Monday that the match means so much for his team because it will determine if they still have a chance or not.。

"This is like a final because Kenya has nothing to lose. They will come with pride and are ready to spoil the party," Sredojevic said.。

Uganda, who will host Harambee Stars at the St. Mary's Stadium, Kitende near the capital Kampala, are second in Group E with 8 points behind Mali who have 10 points.。

"We need to push forward and also be very cautious at the back and defend well because this is not the time to make mistakes," said Sredojevic.。

The team will miss experienced defender Murushid Juuko who is still serving a suspension, while midfielder Tadeo Lwanga who features for Simba SC in the Tanzania Premier League is nursing an injury.。

After the group stage of the FIFA World Cup qualifiers for Africa, 10 teams will compete in the final phase in March 2022 to decide the five slots available for the continent.。

The Ugandan squad has Charles Lukwago, Isma Watenga, Mathias Kigonya, and Joel Mutakubwa as goalkeepers.。

The defenders are Denis Iguma, Gavin Kizito Mugweri, Isaac Muleme, Abdul-Aziizi Kayondo, Timothy Denis Awany, Bevis Mugabi, Livingstone Mulondo, Halid Lwaliwa, Kenneth Semakula, and Geofrey Waswa.。

The midfielders are Khalid Aucho, John Revita, Bobosi Byaruhanga, Mahad Kakooza, Moses Waiswa, Shafik Kuchi Kagimu, Allan Okello, and Julius Poloto.。

The forwards are Fahad Bayo, Yunus Junior Sentamu, Steven Desse Mukwala, Ibrahim Orit, Martin Kizza, and Milton Karisa. Enditem。

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世界首例!猪肾成功移植人体在体外“成活”3天******

  据路透社、《纽约时报》等媒体报道,近日,美国研究团队第一次成功将猪肾移植到人体上,进行实验的54小时中没有发生立即性的免疫系统排斥反应,这被视为一项具有潜力的重大医学突破,最终或许有助于解决人类器官捐献供不应求的情形。

  医生将猪肾连接人体

  猪肾脏在体外“成活”3天

  近日,纽约大学兰贡医疗中心实施了全球首例猪肾移植人体手术。报道称,患者已经脑死亡,患有肾功能失调。她生前希望捐献器官,但出于某些原因无法实现。在医生为她拔除生命维持器前,她的家人同意进行移植猪肾的测试,以这种方式让她为医学研究做出贡献。

  征得患者家属同意后,医生把一个猪肾连接到患者一对大血管上,为方便研究人员近距离观察,猪肾留在患者体外。与患者血管相连后,猪肾正常发挥过滤废物、产生尿液的作用,排尿水平与移植人类肾脏相当。患者手术前肌酐水平异常,在移植后恢复正常。肌酐水平是衡量肾功能是否健全的指标之一。移植手术3天后,患者生命支持设备按预定日期去除。进行手术实验的54小时中没有发生立即性的免疫系统排斥反应。

  主刀医生罗伯特·蒙哥马利表示,猪细胞中一种名为“alpha-gal”的糖分子会引起人体免疫系统的排异反应,会让人体产生严重的过敏反应。而这次手术的“肾源”并非普通的猪,而是经基因改造、去除这种糖分子的猪,它的身体组织内几乎没有可能会立即引发人体免疫系统攻击、造成排斥反应的分子,因此手术没有立即引起排异反应。

  蒙哥马利指出,这颗猪肾能够过滤废物,并制造出和一般移植肾脏相同的预期尿液量,他说:“这比我们预期的结果更好,几乎立刻就开始制造尿液和肌酐废物。很多从死者身上取下的肾脏无法在手术后马上发挥功用,必须花数天或数周才能运作,但这次实验立刻就奏效了。”

  1984年美国一女婴

  移植狒狒心脏活了21天

  将动物器官移植到人类身上代替病变的人体器官,这种治疗方式叫做“异种移植”,其历史可以追溯至17世纪,当时人们试着用动物血输血,但没有成功。

  上世纪60年代左右,人类开始尝试将黑猩猩的肾脏移植到少数人类患者身上,但大多数人不久后便死了,患者中延续生命最长的时间是9个月。1984年,美国一名外科医生尝试将狒狒的心脏移植到人类身上,受试者是一名不到一个月大的女婴,她患有左心发育不全综合症,用狒狒的心脏活了21天,女婴短暂生命和快速死亡引发全球关注。

  由于手术成果无法维持太久,许多人谴责“杀死我们最亲近的动物以拯救自己”的想法,引发伦理争议。于是,科学家们将实验目标从灵长类换到猪身上,并通过修改猪的基因来弥补物种差距。

  报道称,由于猪是人类的食物之一,仅在美国一年就吃掉1.2亿只猪,所以比起猴子或猿类,使用它们的器官进行移植争议相对较少,而且猪一胎的幼崽生产数量较高,怀孕周期也短,猪的器官与人类器官大小、功能等方面都具有相似性。但这个设想实现起来依旧很复杂,早期主要障碍是排异反应,后期则是猪病毒传染的危险。

  美国首次批准基因改造猪上市

  用于生产药品、提供组织和器官移植

  2020年12月,美国食品药品监督管理局首次批准基因改造猪上市,用于生产药品,提供移植组织和器官。

  基因改造猪由美国联合医疗公司旗下子品牌打造,被称为“GalSafe猪”。这种猪目前约有100头,以严格控制的条件饲育于美国的爱荷华州。这次移植手术使用的基因改造猪就来自这里。

  不过,美国食药监局表示,如果以“GalSafe猪”开发的医疗产品要应用于人体或者将其纳入移植器官选项之一,还是得再次经过他们的特别许可才能正式上路。

  或将突破器官供应难题

  可能一两年内纳入医疗领域

  根据美国非营利组织“器官共享联合网络”的数据显示,在美国,约10.7万人在等待器官移植,其中有9万人是在等待肾脏,通常必须要排队三到五年才有可能获得机会,因此每天都有12人久候不及去世。美国目前有超过50万名的肾衰竭患者,只能依靠洗肾维持身体机能,他们基本上是没有资格接受移植手术的,因为器官捐赠的数量实在太过稀少,必须优先留给最有可能在手术后健康存活的人。

  因此,想方设法从别的来源取得器官成为人类发展医疗领域的要务之一。科学家此前已成功使用猪心瓣膜和胰腺做人体组织的替代物。猪皮也可以帮助烧伤病人进行植皮手术,抗凝血的肝素也是从猪肠中萃取出来的。

  报道称,猪肾移植到人体无排异反应这一实验具有里程碑意义,被视为一项具有潜力的重大医学突破。最终或许有助于解决人类器官捐献供不应求,导致每年有无数病患在等待中抱憾而终的情形。专家们希望这项技术未来有一天能够解决全球器官捐献严重短缺的困境。

  “对肾病患者中的很多人来说,他们的死亡率跟一些癌症一样高,而无论是使用新药物或是进行新实验,我们在面对癌症患者时都不会考虑太多,因为这或许可以让他们再多活上几个月。”蒙哥马利说,本次研究或许将造福肾衰竭晚期的患者,而且可能在一两年内就可以正式纳入医疗领域。“目前实验只让猪肾运行了不到3天,来可能发现必须被克服的新障碍。”

  “器官共享联合网络”负责人克拉森表示,这次实验可以说是创造了一个分水岭。但他同时表示,就算人与人之间的器官移植在匹配度良好状况下还会发生长期器官排斥反应,更何况如今还是跨越物种案例。肾脏可不只有清除血液中的废物与毒素的功能,接受移植的患者也有可能在手术后感染猪的病毒。华商报记者 郭霁 编译


来源:华商网-华商报

编辑:唐港

Madagascar minister swims 12 hours to shore after helicopter crash******

A Madagascan minister was one of two survivors who swam 12 hours to shore on Tuesday after their helicopter crashed off the island's northeastern coast, authorities said.。

A search was continuing for two other passengers after the crash on Monday, the cause of which was not immediately clear, police and port authorities said.。

Serge Gelle, the country's secretary of state for police, and a fellow policeman reached land in the seaside town of Mahambo separately on Tuesday morning, apparently after ejecting themselves from the aircraft, port authority chief Jean-Edmond Randrianantenaina said.。

In a video shared on social media, 57-year-old Gelle appears lying exhausted on a deck chair, still in his camouflage uniform.。

"My time to die hasn't come yet," says the general, adding he was cold but not injured.。

The helicopter was flying him and the others to inspect the site of a shipwreck off the northeastern coast on Monday morning. At least 39 people died in that disaster, police chief Zafisambatra Ravoavy said on Tuesday, in an increase from a previous toll after rescue workers retrieved 18 more bodies.。

Ravoavy said Gelle had used one of the helicopter's seats as a flotation device.。

"He has always had great stamina in sport, and he's kept up this rhythm as minister, just like a thirty-year-old," he said.。

"He has nerves of steel."

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